UC Berkeley School of Public Health
Division of Infectious Disease & Vaccinology

Josefina Coloma, PhD

Josefina Coloma, PhD

Faculty Researcher
Exec. Director, Sustainable sciences institute (SSI)
PhD, UC Los Angeles

Ecuador

colomaj (at) berkeley (dot) edu

Robert Beatty, PhD

Robert Beatty, PhD

Faculty Collaborator
Lecturer of immunology, mCB
PhD, UC Berkeley

prbeatty (at) berkeley (dot) edu

 I am a molecular virologist. I got my Ph.D. degree in Molecular Genetics and Microbiology from State University of New York, Stony Brook University. I studied picornavirus morphogenesis for my Ph.D. thesis in Dr. Eckard Wimmer’s lab. My passion for molecular biology and infectious diseases led me to the flavivirus field here at Harris lab in Cal back in 2013.  My current project focuses on revealing the molecular determinant of NS1-induced endothelial cell hyperpermeability. Our work identifies NS1-N207 as a residue conserved among multiple flaviviruses (Zika virus and West Nile virus, in addition to DENV), which is critical for NS1-mediated vascular leak in biologically relevant endothelial cells. We also identified the NS1 binding determinant to endothelial cells. These new knowledge are critical for understanding pan-flavivirus pathogenesis, representing a novel target for anti-flaviviral therapy, and shed light on development of NS1-based subunit vaccine.  I like gardening, bicycling and cooking dumplings.  “Keep true to the dreams of thy youth” – Friedrich Schiller

I am a molecular virologist. I got my Ph.D. degree in Molecular Genetics and Microbiology from State University of New York, Stony Brook University. I studied picornavirus morphogenesis for my Ph.D. thesis in Dr. Eckard Wimmer’s lab. My passion for molecular biology and infectious diseases led me to the flavivirus field here at Harris lab in Cal back in 2013.

My current project focuses on revealing the molecular determinant of NS1-induced endothelial cell hyperpermeability. Our work identifies NS1-N207 as a residue conserved among multiple flaviviruses (Zika virus and West Nile virus, in addition to DENV), which is critical for NS1-mediated vascular leak in biologically relevant endothelial cells. We also identified the NS1 binding determinant to endothelial cells. These new knowledge are critical for understanding pan-flavivirus pathogenesis, representing a novel target for anti-flaviviral therapy, and shed light on development of NS1-based subunit vaccine.

I like gardening, bicycling and cooking dumplings.

“Keep true to the dreams of thy youth” – Friedrich Schiller

Chunling Wang, PhD

Assistant Project Scientist
PhD, SUNY Stony Brook

Tai’an, Shandong, China

chunlingwang (at) berkeley (dot) edu

 I joined Dr. Eva Harris Lab in February 2013 as a Postdoctoral fellow at the School of Public Health. I am interested in elucidating the mechanisms for pathogenesis of distinct arthropod-transmitted viruses such as Dengue virus, Zika virus, WNV virus (Kunjin virus) from a basic perspective.  In the Harris Lab, I study the effect of the Non structural protein-1 (NS1) of the Flavivirus genus on the biology of endothelial cells that results in disruption/malfunction of the endothelial glycocalyx and the intercellular junction complex leading to vascular leakage and virus dissemination.  My goal is to translate these basic research into a community-based studies in Latinoamerica. I love spending time with my wife and my dog, playing soccer, and resting at home having coffee/dessert :).

I joined Dr. Eva Harris Lab in February 2013 as a Postdoctoral fellow at the School of Public Health. I am interested in elucidating the mechanisms for pathogenesis of distinct arthropod-transmitted viruses such as Dengue virus, Zika virus, WNV virus (Kunjin virus) from a basic perspective.

In the Harris Lab, I study the effect of the Non structural protein-1 (NS1) of the Flavivirus genus on the biology of endothelial cells that results in disruption/malfunction of the endothelial glycocalyx and the intercellular junction complex leading to vascular leakage and virus dissemination.

My goal is to translate these basic research into a community-based studies in Latinoamerica. I love spending time with my wife and my dog, playing soccer, and resting at home having coffee/dessert :).

Henry Puerta-Guardo, PhD

Postdoctoral Fellow
PhD, National Polytechnic Institute, Mexico

Cartagena de Indias, Bolívar, Colombia

hpuertaguardo (at) berkeley (dot) edu

 I am an immunologist with a primary interest in infectious diseases and vaccinology. I earned my PhD from Johns Hopkins University, where I developed chimeric malaria parasites for the preclinical evaluation of vaccine candidates.  I joined the Harris Lab in 2015 and my projects currently involve assessing immune responses induced by non-structural 1 (NS1) protein immunizations, characterizing NS1-induced mechanisms of flavivirus pathogenesis, and identifying host biomarkers associated with severe dengue disease.  Outside the lab, I enjoy spending time with my family, making new friends and exploring the outdoors.

I am an immunologist with a primary interest in infectious diseases and vaccinology. I earned my PhD from Johns Hopkins University, where I developed chimeric malaria parasites for the preclinical evaluation of vaccine candidates.

I joined the Harris Lab in 2015 and my projects currently involve assessing immune responses induced by non-structural 1 (NS1) protein immunizations, characterizing NS1-induced mechanisms of flavivirus pathogenesis, and identifying host biomarkers associated with severe dengue disease.

Outside the lab, I enjoy spending time with my family, making new friends and exploring the outdoors.

Diego Espinosa, PhD

Postdoctoral Fellow
PhD, Johns Hopkins University

Lima, Peru

despinosa (at) berkeley (dot) edu

 I have conducted my PhD in the UK at the University of Glasgow studying the role of chemokines in the pathogenesis of viral encephalitis. Next I moved to New York city where I conducted my first Post doc in the lab of Dr. Jean Lim. In her lab I was working on the role of CCR5 during tick borne encephalitis virus infection and also investigated the role of monocytes in a mouse model of West Nile virus encephalitis.  I joined the Harris lab in November 2015 for my second post doc and I am now a member of the human immunology group. My main focus is to study the innate immune profile during dengue, Zika and chikungunya virus infection in pediatric cohort and hospital samples from Nicaragua. I am using a systems immunology approach to answer this question. Furthermore, I am also investigating the memory B cell response in clinical trial samples for a live-attenuated dengue vaccine developed by Takeda pharmaceuticals.  As a side project, I have also gained hand-on experience with diagnostic assays including the dengue and chikungunya inhibition ELISA and the Zika NS1-BOB assay. I am using these assays to conduct a seroprevalence study in the South of Ethiopia to identify the burden of arboviral infections. Furthermore I am also involved in lab-capacity building in Ethiopia as I am extremely passionate about global health.

I have conducted my PhD in the UK at the University of Glasgow studying the role of chemokines in the pathogenesis of viral encephalitis. Next I moved to New York city where I conducted my first Post doc in the lab of Dr. Jean Lim. In her lab I was working on the role of CCR5 during tick borne encephalitis virus infection and also investigated the role of monocytes in a mouse model of West Nile virus encephalitis.

I joined the Harris lab in November 2015 for my second post doc and I am now a member of the human immunology group. My main focus is to study the innate immune profile during dengue, Zika and chikungunya virus infection in pediatric cohort and hospital samples from Nicaragua. I am using a systems immunology approach to answer this question. Furthermore, I am also investigating the memory B cell response in clinical trial samples for a live-attenuated dengue vaccine developed by Takeda pharmaceuticals.

As a side project, I have also gained hand-on experience with diagnostic assays including the dengue and chikungunya inhibition ELISA and the Zika NS1-BOB assay. I am using these assays to conduct a seroprevalence study in the South of Ethiopia to identify the burden of arboviral infections. Furthermore I am also involved in lab-capacity building in Ethiopia as I am extremely passionate about global health.

Daniela Michlmayr, PhD

Postdoctoral Fellow
PhD, University of Glasgow

Innsbruck, Austria

dmic (at) berkeley (dot) edu

Leah Katzelnick, PhD

Leah Katzelnick, PhD

Postdoctoral Fellow
Global Health Equity Scholar
PhD, Cambridge University

Madison, Wisconsin

leah.katzelnick (at) berkeley (dot) edu

 I’m a visiting scholar at Harris Lab from University of São Paulo, Brazil. I have been studying the mechanism of antiviral action of natural and semi-synthetic compounds. My current research interests include dengue pathogenesis and search for antivirals to prevent/treat flavivirus infections.  The best free time for me is spent outdoors specially on the beach with my son. I prefer to be with family and friends than by myself.

I’m a visiting scholar at Harris Lab from University of São Paulo, Brazil. I have been studying the mechanism of antiviral action of natural and semi-synthetic compounds. My current research interests include dengue pathogenesis and search for antivirals to prevent/treat flavivirus infections.

The best free time for me is spent outdoors specially on the beach with my son. I prefer to be with family and friends than by myself.

Francielle Tramontini, PhD

Visiting Fellow
PhD, UF Santa Catarina

Florianópolis, SC, Brazil

francilletg (at) gmail (dot) com

 I am a molecular virologist and immunologist with a passion for understanding viral-host interactions. I conducted my undergraduate studies with Dr. Benhur Lee and Dr. Hector Aguilar-Carreno at UCLA, studying entry mechanisms of the deadly nipah virus. I obtained my PhD from the University of Chicago with Dr. Seungmin “Sam” Hwang studying antiviral mechanisms of interferon gamma and investigating viral triggers of complex autoimmune disorders such as celiac disease. In the Harris lab I am investigating the role of the flaviviral NS1 proteins in inducing viral pathogenesis. My approach is to characterize how NS1 modulates endothelial cells to trigger endothelial hyperpermeability. I’m currently focused on identifying host factors required for NS1-induced endothelial hyperpermeability, which is critical for understanding the mechanism(s) behind this process. Outside of lab I enjoy spending time with friends and family, traveling, and hiking.

I am a molecular virologist and immunologist with a passion for understanding viral-host interactions. I conducted my undergraduate studies with Dr. Benhur Lee and Dr. Hector Aguilar-Carreno at UCLA, studying entry mechanisms of the deadly nipah virus. I obtained my PhD from the University of Chicago with Dr. Seungmin “Sam” Hwang studying antiviral mechanisms of interferon gamma and investigating viral triggers of complex autoimmune disorders such as celiac disease. In the Harris lab I am investigating the role of the flaviviral NS1 proteins in inducing viral pathogenesis. My approach is to characterize how NS1 modulates endothelial cells to trigger endothelial hyperpermeability. I’m currently focused on identifying host factors required for NS1-induced endothelial hyperpermeability, which is critical for understanding the mechanism(s) behind this process. Outside of lab I enjoy spending time with friends and family, traveling, and hiking.

Scott Biering, PhD

Postdoctoral Fellow
PhD, University of Chicago

Frazier Park, California

sbiering (at) berkeley (dot) edu

 

GRADUATE STUDENTS

 I am a doctoral student at the infectious Disease and Immunity program. I joined the Harris lab 4 years ago.  I love to study human immunology in the context of infectious diseases, particularly B cell responses. My project aims to understand the development of type-specific and cross-reactive B cell responses in patients who have been infected with either Zika, dengue or with both viruses. I am focused on memory B cells (MBC) and at our projects we are studying quantitatively and qualitatively antibodies produced by MBC and we are trying to understand how these antibodies correlate with antibodies from serum responses that come from plasma cells.  I am passionate about working in Global Health concerns and about  giving back to the community. My other passions are dancing, hiking, yoga and sharing the best quality time with my people.

I am a doctoral student at the infectious Disease and Immunity program. I joined the Harris lab 4 years ago.  I love to study human immunology in the context of infectious diseases, particularly B cell responses. My project aims to understand the development of type-specific and cross-reactive B cell responses in patients who have been infected with either Zika, dengue or with both viruses. I am focused on memory B cells (MBC) and at our projects we are studying quantitatively and qualitatively antibodies produced by MBC and we are trying to understand how these antibodies correlate with antibodies from serum responses that come from plasma cells.  I am passionate about working in Global Health concerns and about  giving back to the community. My other passions are dancing, hiking, yoga and sharing the best quality time with my people.

Paulina Andrade

PhD Candidate
MS, Wageningen University

Quito, Ecuador

paulinaandradeproano (at) berkeley (dot) edu

 I’m a sixth year PhD Candidate in the Infectious Diseases and Immunity program. My interest for translational science dates back from my Masters Degree work at UFMG (Brazil), where I immunoprofiled the T cell and cytokine response of Chagas-infected patients.  In the Harris Lab, my research aims at mapping the neutralizing antibody response to natural dengue virus infection. I am particularly excited about our studies because it is very multidisciplinary and has direct impact on dengue vaccine design. Outside the lab, I enjoy hiking trails along the Pacific Coast, ice-cream tasting, photography and stand-up comedy.

I’m a sixth year PhD Candidate in the Infectious Diseases and Immunity program. My interest for translational science dates back from my Masters Degree work at UFMG (Brazil), where I immunoprofiled the T cell and cytokine response of Chagas-infected patients.

In the Harris Lab, my research aims at mapping the neutralizing antibody response to natural dengue virus infection. I am particularly excited about our studies because it is very multidisciplinary and has direct impact on dengue vaccine design. Outside the lab, I enjoy hiking trails along the Pacific Coast, ice-cream tasting, photography and stand-up comedy.

Daniela Andrade

PHD CANDIDATE
MS, UF Minas Gerais

Belo Horizonte, MG, Brazil

andrade.danielav (at) gmail (dot) com

 I am an epidemiologist and biostatistician in training. I am primarily interested in computationally intensive epidemiological analyses of infectious diseases in tropical settings.  For the last 4 years, I have been analyzing the epidemiological and spatio-temporal dimensions to dengue virus, chikungunya virus, and Zika virus infections and instances of disease manifestation in a large pediatric cohort in Managua, Nicaragua.  My research combines traditional epidemiological techniques with modern biostatistical and data-adaptive methods. In my spare time, I can be found geeking out to anime, reading piles of books, baking, and trying to become Twitter famous.

I am an epidemiologist and biostatistician in training. I am primarily interested in computationally intensive epidemiological analyses of infectious diseases in tropical settings.

For the last 4 years, I have been analyzing the epidemiological and spatio-temporal dimensions to dengue virus, chikungunya virus, and Zika virus infections and instances of disease manifestation in a large pediatric cohort in Managua, Nicaragua.

My research combines traditional epidemiological techniques with modern biostatistical and data-adaptive methods. In my spare time, I can be found geeking out to anime, reading piles of books, baking, and trying to become Twitter famous.

Fausto Bustos

PhD Candidate
SM, Harvard University

Tijuana, Mexico

fbustos (at) berkeley (dot) edu

 I am a PhD student in the Infectious Diseases & Immunity program. Prior to Berkeley, I studied biology and international relations at Boston College and graduated in 2016, where I worked on Toxoplasma gondii and got very fascinated with host-pathogen interactions and pathogenesis.  In the Harris lab, I work on the viral determinants of flavivirus’ non-structural protein 1 (NS1) in binding and internalisation. Outside of lab I enjoy rock climbing, hiking, and eating my way through a foreign city.

I am a PhD student in the Infectious Diseases & Immunity program. Prior to Berkeley, I studied biology and international relations at Boston College and graduated in 2016, where I worked on Toxoplasma gondii and got very fascinated with host-pathogen interactions and pathogenesis.

In the Harris lab, I work on the viral determinants of flavivirus’ non-structural protein 1 (NS1) in binding and internalisation. Outside of lab I enjoy rock climbing, hiking, and eating my way through a foreign city.

Nicholas Lo

PhD Researcher
BS, BOston College

Singapore & Taipei, Taiwan

nicholas.lo (at) berkeley (dot) edu

LAB STAFF

Magelda Montoya

Magelda Montoya

Assistant Specialist
BS, National Autonomous University of Nicaragua

Matagalpa, Nicaragua

mageldamontoya (at) gmail (dot) com

 I am two years out of Brandeis University, majoring in Health: Science, Society, and Policy.  I am currently helping out the immunology team, running assays to analyze dengue virus and the neutralizing antibodies involved. I am also particularly interested in bioinformatics and public health.  In my free time, I am an avid follower of soccer and basketball, primarily Everton FC, the best team in England. I am an avid runner, hiker, camper, and biker, pretty much anything outdoor and a part time philosopher.

I am two years out of Brandeis University, majoring in Health: Science, Society, and Policy.

I am currently helping out the immunology team, running assays to analyze dengue virus and the neutralizing antibodies involved. I am also particularly interested in bioinformatics and public health.

In my free time, I am an avid follower of soccer and basketball, primarily Everton FC, the best team in England. I am an avid runner, hiker, camper, and biker, pretty much anything outdoor and a part time philosopher.

Colin Warnes

LAB MANAGER & Technician
BS, Brandeis University

San Jose, California

cwarnes (at) berkeley (dot) edu

Parnal Narvekar

Parnal Narvekar

Research Associate
MS, University of Illinois at Chicago

Mumbai, Maharashtra, India

parnal.narvekar (at) berkeley (dot) edu

Mark Patana

Mark Patana

Lab Technician
BA, UC Berkeley

Los Angeles, California

markpatana (at) berkeley (dot) edu

UNDERGRADUATE RESEARCHERS

Trent A. Gomberg

Trent A.
Gomberg

Mcb immuno, ‘19

Seal Beach, CA

tagomberg (at) berkeley (dot) edu

Kendall E. Lee

Kendall E.
Lee

Public Health, ‘19

Menlo Park, CA

kendall.lee (at) berkeley (dot) edu

Kyle Gibson

Kyle
Gibson

public health, ‘19

Riverside, CA

kyle.gibson (at) berkeley (dot) edu

Kerri Yen

Kerri
Yen

MCB Immuno, ‘19

San Jose, CA

kyen (at) berkeley (dot) edu

Ife Desamours

Ife
Desamours

microbiology, ‘19

Budapest, Hungary

idesamours (at) berkeley (dot) edu

Jeffrey Li

Jeffrey
Li

Public Health, ‘20

Miami, FL

jeff.li (at) berkeley (dot) edu

Laura Gomez

Laura
Gomez

Mcb immuno, ‘20

Bogotá, Colombia

lauracgm98 (at) berkeley (dot) edu

Jasmine Larrick

Jasmine
Larrick

MCB Biochem, ‘20

Woodside, CA

jasminewlarrick (at) berkeley (dot) edu

Anthony Mauriello
 
 
 

Anthony
Mauriello

MCB IMMUNO, ‘21

Mountain View, CA

anthony.mauriello (at) berkeley (dot) edu